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Cefiderocol therapy among immunocompromised adult patients: a descriptive analysis from a prospective, multicentre cohort study.

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Title: Cefiderocol therapy among immunocompromised adult patients: a descriptive analysis from a prospective, multicentre cohort study.
Authors: Lombardi A; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy., Giacobbe DR; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. danieleroberto.giacobbe@unige.it.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. danieleroberto.giacobbe@unige.it., Mangioni D; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy., Mariani B; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy., Muscatello A; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy., Muccio M; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Aldieri C; Infectious Diseases Unit, S. Croce E Carle Hospital, Cuneo, Italy., Briano F; SC Malattie Infettive E Tropicali, Ospedale San Paolo Savona, Savona, Italy., Cacopardo B; Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy., Calabresi A; AOU SS Antonio, Biagio e Cesare Arrigo, Alessandria, Italy., Capra Marzani F; SC AR1-Terapia Intensiva Generale, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Carretta A; Department of Medical and Surgical Sciences, Infectious Diseases Unit, University of Foggia, Foggia, Italy., Cattelan A; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy., Ceccarelli L; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; Department of Integrated Management of Infectious Risk, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Policlinico Sant'Orsola, Bologna, Italy., Cenderello G; Department of Infectious Diseases, Sanremo Hospital, Sanremo, Italy., Corcione S; Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.; Tufts University School of Medicine, Boston, MA, USA., Cortegiani A; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy.; Department of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, Palermo, Italy., Cultrera R; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Infectious Diseases, Azienda Unità Sanitaria Locale of Ferrara, Ferrara, Italy., De Rosa FG; Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy., Del Bono V; Infectious Diseases Unit, S. Croce E Carle Hospital, Cuneo, Italy., Del Puente F; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Fanelli C; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Fava F; Anestesia E Terapia Intensiva Cardiotoracica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Francisci D; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy., Geremia N; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale 'Dell'Angelo', Venice, Italy.; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale Civile 'S.S. Giovanni E Paolo', Venice, Italy., Graziani L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Losito AR; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy., Maida I; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Marino A; Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy., Mazzitelli M; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy., Merli M; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Monardo R; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Mularoni A; IRCCS-ISMETT, Palermo, Italy., Oltolini C; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Pallotto C; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy., Pontali E; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Raffaelli F; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy., Rinaldi M; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; Department of Integrated Management of Infectious Risk, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Policlinico Sant'Orsola, Bologna, Italy., Ripa M; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Santantonio TA; Department of Medical and Surgical Sciences, Infectious Diseases Unit, University of Foggia, Foggia, Italy., Serino FS; Azienda ULSS4 Veneto Orientale, UOS Malattie Infettive, UOC Medicina Generale Portogruaro, Portogruaro, Italy., Spinicci M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Torti C; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy.; Dipartimento Di Sicurezza E Bioetica, Università Cattolica del Sacro Cuore, Sez. Malattie Infettive, Rome, Italy., Trecarichi EM; Department of Life Science, Health, and Health Professions, Link Campus University, Rome, Italy.; Department of Medical and Surgical Sciences, University 'Magna Graecia', Catanzaro, Italy.; 'R. Dulbecco' Teaching Hospital, Catanzaro, Italy., Tumbarello M; Department of Medical Biotechnologies, University of Siena, Siena, Italy.; Infectious and Tropical Diseases Unit, Azienda Ospedaliero Universitaria Senese, Siena, Italy., Mikulska M; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Vena A; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bandera A; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy., Bassetti M; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Corporate Authors: CEFI-SITA investigators
Source: BMC infectious diseases [BMC Infect Dis] 2025 Oct 16; Vol. 25 (1), pp. 1339. Date of Electronic Publication: 2025 Oct 16.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
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  Data: Cefiderocol therapy among immunocompromised adult patients: a descriptive analysis from a prospective, multicentre cohort study.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Lombardi+A%22">Lombardi A</searchLink>; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giacobbe+DR%22">Giacobbe DR</searchLink>; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. danieleroberto.giacobbe@unige.it.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. danieleroberto.giacobbe@unige.it.<br /><searchLink fieldCode="AU" term="%22Mangioni+D%22">Mangioni D</searchLink>; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mariani+B%22">Mariani B</searchLink>; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Muscatello+A%22">Muscatello A</searchLink>; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Muccio+M%22">Muccio M</searchLink>; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Aldieri+C%22">Aldieri C</searchLink>; Infectious Diseases Unit, S. Croce E Carle Hospital, Cuneo, Italy.<br /><searchLink fieldCode="AU" term="%22Briano+F%22">Briano F</searchLink>; SC Malattie Infettive E Tropicali, Ospedale San Paolo Savona, Savona, Italy.<br /><searchLink fieldCode="AU" term="%22Cacopardo+B%22">Cacopardo B</searchLink>; Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Calabresi+A%22">Calabresi A</searchLink>; AOU SS Antonio, Biagio e Cesare Arrigo, Alessandria, Italy.<br /><searchLink fieldCode="AU" term="%22Capra+Marzani+F%22">Capra Marzani F</searchLink>; SC AR1-Terapia Intensiva Generale, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Carretta+A%22">Carretta A</searchLink>; Department of Medical and Surgical Sciences, Infectious Diseases Unit, University of Foggia, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Cattelan+A%22">Cattelan A</searchLink>; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Ceccarelli+L%22">Ceccarelli L</searchLink>; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; Department of Integrated Management of Infectious Risk, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Policlinico Sant'Orsola, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Cenderello+G%22">Cenderello G</searchLink>; Department of Infectious Diseases, Sanremo Hospital, Sanremo, Italy.<br /><searchLink fieldCode="AU" term="%22Corcione+S%22">Corcione S</searchLink>; Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.; Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cortegiani+A%22">Cortegiani A</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy.; Department of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Cultrera+R%22">Cultrera R</searchLink>; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Infectious Diseases, Azienda Unità Sanitaria Locale of Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22De+Rosa+FG%22">De Rosa FG</searchLink>; Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Bono+V%22">Del Bono V</searchLink>; Infectious Diseases Unit, S. Croce E Carle Hospital, Cuneo, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Puente+F%22">Del Puente F</searchLink>; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Fanelli+C%22">Fanelli C</searchLink>; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.<br /><searchLink fieldCode="AU" term="%22Fava+F%22">Fava F</searchLink>; Anestesia E Terapia Intensiva Cardiotoracica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Francisci+D%22">Francisci D</searchLink>; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Geremia+N%22">Geremia N</searchLink>; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale 'Dell'Angelo', Venice, Italy.; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale Civile 'S.S. Giovanni E Paolo', Venice, Italy.<br /><searchLink fieldCode="AU" term="%22Graziani+L%22">Graziani L</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Losito+AR%22">Losito AR</searchLink>; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Maida+I%22">Maida I</searchLink>; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.<br /><searchLink fieldCode="AU" term="%22Marino+A%22">Marino A</searchLink>; Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzitelli+M%22">Mazzitelli M</searchLink>; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Merli+M%22">Merli M</searchLink>; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Monardo+R%22">Monardo R</searchLink>; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mularoni+A%22">Mularoni A</searchLink>; IRCCS-ISMETT, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Oltolini+C%22">Oltolini C</searchLink>; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pallotto+C%22">Pallotto C</searchLink>; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Pontali+E%22">Pontali E</searchLink>; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Raffaelli+F%22">Raffaelli F</searchLink>; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rinaldi+M%22">Rinaldi M</searchLink>; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; Department of Integrated Management of Infectious Risk, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Policlinico Sant'Orsola, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ripa+M%22">Ripa M</searchLink>; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Santantonio+TA%22">Santantonio TA</searchLink>; Department of Medical and Surgical Sciences, Infectious Diseases Unit, University of Foggia, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Serino+FS%22">Serino FS</searchLink>; Azienda ULSS4 Veneto Orientale, UOS Malattie Infettive, UOC Medicina Generale Portogruaro, Portogruaro, Italy.<br /><searchLink fieldCode="AU" term="%22Spinicci+M%22">Spinicci M</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Torti+C%22">Torti C</searchLink>; Dipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Malattie Infettive, Rome, Italy.; Dipartimento Di Sicurezza E Bioetica, Università Cattolica del Sacro Cuore, Sez. Malattie Infettive, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Trecarichi+EM%22">Trecarichi EM</searchLink>; Department of Life Science, Health, and Health Professions, Link Campus University, Rome, Italy.; Department of Medical and Surgical Sciences, University 'Magna Graecia', Catanzaro, Italy.; 'R. Dulbecco' Teaching Hospital, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Tumbarello+M%22">Tumbarello M</searchLink>; Department of Medical Biotechnologies, University of Siena, Siena, Italy.; Infectious and Tropical Diseases Unit, Azienda Ospedaliero Universitaria Senese, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Mikulska+M%22">Mikulska M</searchLink>; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Vena+A%22">Vena A</searchLink>; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Bandera+A%22">Bandera A</searchLink>; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bassetti+M%22">Bassetti M</searchLink>; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy and Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
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  Data: <searchLink fieldCode="JN" term="%22100968551%22">BMC infectious diseases</searchLink> [BMC Infect Dis] 2025 Oct 16; Vol. 25 (1), pp. 1339. <i>Date of Electronic Publication: </i>2025 Oct 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100968551 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2334 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712334%22">14712334 </searchLink><i>NLM ISO Abbreviation: </i>BMC Infect Dis <i>Subsets: </i>MEDLINE
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          Name:
            NameFull: Rinaldi M
      – PersonEntity:
          Name:
            NameFull: Ripa M
      – PersonEntity:
          Name:
            NameFull: Santantonio TA
      – PersonEntity:
          Name:
            NameFull: Serino FS
      – PersonEntity:
          Name:
            NameFull: Spinicci M
      – PersonEntity:
          Name:
            NameFull: Torti C
      – PersonEntity:
          Name:
            NameFull: Trecarichi EM
      – PersonEntity:
          Name:
            NameFull: Tumbarello M
      – PersonEntity:
          Name:
            NameFull: Mikulska M
      – PersonEntity:
          Name:
            NameFull: Vena A
      – PersonEntity:
          Name:
            NameFull: Bandera A
      – PersonEntity:
          Name:
            NameFull: Bassetti M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 10
              Text: 2025 Oct 16
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1471-2334
          Numbering:
            – Type: volume
              Value: 25
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: BMC infectious diseases
              Type: main
ResultId 1