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Tailor-made 3D in vitro maturation of early antral follicles uncovers cumulus-cell transcriptomic driver signature to predict oocyte competence.

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Title: Tailor-made 3D in vitro maturation of early antral follicles uncovers cumulus-cell transcriptomic driver signature to predict oocyte competence.
Authors: Rojo-Fleming C; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Konstantinidou F; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Peserico A; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Di Berardino C; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Capacchietti G; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Nardinocchi D; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Camerano Spelta Rapini C; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Russo V; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Bernabò N; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Capalbo A; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Stuppia L; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Gatta V; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Barboni B; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Oct 01; Vol. 16, pp. 1629815. Date of Electronic Publication: 2025 Oct 01 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tailor-made 3D in vitro maturation of early antral follicles uncovers cumulus-cell transcriptomic driver signature to predict oocyte competence.
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  Data: <searchLink fieldCode="AU" term="%22Rojo-Fleming+C%22">Rojo-Fleming C</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Konstantinidou+F%22">Konstantinidou F</searchLink>; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Peserico+A%22">Peserico A</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Berardino+C%22">Di Berardino C</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Capacchietti+G%22">Capacchietti G</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Nardinocchi+D%22">Nardinocchi D</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Camerano+Spelta+Rapini+C%22">Camerano Spelta Rapini C</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Russo+V%22">Russo V</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Bernabò+N%22">Bernabò N</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.<br /><searchLink fieldCode="AU" term="%22Capalbo+A%22">Capalbo A</searchLink>; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Stuppia+L%22">Stuppia L</searchLink>; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Gatta+V%22">Gatta V</searchLink>; Department of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Barboni+B%22">Barboni B</searchLink>; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.
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