Adjuvant nivolumab and relatlimab in stage III/IV melanoma: the randomized phase 3 RELATIVITY-098 trial.

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Title: Adjuvant nivolumab and relatlimab in stage III/IV melanoma: the randomized phase 3 RELATIVITY-098 trial.
Authors: Long GV; Melanoma Institute Australia, The University of Sydney, Royal North Shore and Mater Hospitals, Sydney, New South Wales, Australia. georgina.long@sydney.edu.au., Garnett-Benson C; Bristol Myers Squibb, Princeton, NJ, USA., Dolfi S; Bristol Myers Squibb, Princeton, NJ, USA., Ascierto PA; Istituto Nazionale dei Tumori IRCCS 'Fondazione G. Pascale', Napoli, Italy., Guo J; Peking University Cancer Hospital & Institute, Beijing, China., Tarhini AA; Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Chandra S; Northwestern University, Chicago, IL, USA., Muñoz-Couselo E; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Del Vecchio M; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., de Melo AC; Brazilian National Cancer Institute, Rio de Janeiro, Brazil., Callahan M; Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gogas H; National and Kapodistrian University of Athens, Athens, Greece., Dummer R; University of Zurich, Zurich, Switzerland., Schadendorf D; University Hospital Essen, National Center for Tumor Diseases (NCT-West), Campus Essen, German Cancer Consortium, Campus Essen, and University Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Essen, Germany., Koelblinger P; Paracelsus Medical University, Salzburg, Austria., Quereux G; CHU Nantes, Nantes University and Immunology and New Concepts in ImmunoTherapy (INCIT), Nantes, France., Thomas I; EDOEAP, Athens, Greece., Yu JX; Bristol Myers Squibb, Princeton, NJ, USA., Fisher A; Bristol Myers Squibb, Princeton, NJ, USA., Wang B; Bristol Myers Squibb, Princeton, NJ, USA., Djidel P; Bristol Myers Squibb, Princeton, NJ, USA., Chouzy A; Bristol Myers Squibb, Princeton, NJ, USA., Semaan M; Bristol Myers Squibb, Princeton, NJ, USA., Chen B; Bristol Myers Squibb, Princeton, NJ, USA., Cheong AMY; Bristol Myers Squibb, Uxbridge, UK., Tawbi HA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Source: Nature medicine [Nat Med] 2025 Dec; Vol. 31 (12), pp. 4301-4309. Date of Electronic Publication: 2025 Oct 18.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-170X
DOI:10.1038/s41591-025-04032-8