Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
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| Title: | Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation. |
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| Authors: | Harit K; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Yi W; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Jeron A; Institute of Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University Magdeburg, Magdeburg, Germany., Schmidt J; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Beckervordersandforth R; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Wyler E; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Manukyan A; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Deckert M; Department of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Radbruch H; Institute of Neuropathology, Charité-University Medicine Berlin, Institute of Neuropathology, Berlin, Germany., Conrad T; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany., Altmüller J; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Berlin Institute of Health at Charité, Berlin, Germany., Landthaler M; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Institut für Biologie, Humboldt-Universität zu Berlin, Berlin, Germany., Wang X; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Nishanth G; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Schlüter D; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de.; Cluster of Excellence-Resolving Infection Susceptibility (RESIST), (EXC 2155), Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de. |
| Source: | Nature communications [Nat Commun] 2025 Oct 20; Vol. 16 (1), pp. 9279. Date of Electronic Publication: 2025 Oct 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65093-4 |
