Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.

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Title: Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
Authors: Harit K; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Yi W; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Jeron A; Institute of Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University Magdeburg, Magdeburg, Germany., Schmidt J; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Beckervordersandforth R; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Wyler E; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Manukyan A; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Deckert M; Department of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Radbruch H; Institute of Neuropathology, Charité-University Medicine Berlin, Institute of Neuropathology, Berlin, Germany., Conrad T; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany., Altmüller J; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Berlin Institute of Health at Charité, Berlin, Germany., Landthaler M; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Institut für Biologie, Humboldt-Universität zu Berlin, Berlin, Germany., Wang X; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Nishanth G; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Schlüter D; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de.; Cluster of Excellence-Resolving Infection Susceptibility (RESIST), (EXC 2155), Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de.
Source: Nature communications [Nat Commun] 2025 Oct 20; Vol. 16 (1), pp. 9279. Date of Electronic Publication: 2025 Oct 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Harit+K%22">Harit K</searchLink>; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Yi+W%22">Yi W</searchLink>; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Jeron+A%22">Jeron A</searchLink>; Institute of Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+J%22">Schmidt J</searchLink>; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Beckervordersandforth+R%22">Beckervordersandforth R</searchLink>; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Wyler+E%22">Wyler E</searchLink>; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Manukyan+A%22">Manukyan A</searchLink>; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Deckert+M%22">Deckert M</searchLink>; Department of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Radbruch+H%22">Radbruch H</searchLink>; Institute of Neuropathology, Charité-University Medicine Berlin, Institute of Neuropathology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Conrad+T%22">Conrad T</searchLink>; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Altmüller+J%22">Altmüller J</searchLink>; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Berlin Institute of Health at Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Landthaler+M%22">Landthaler M</searchLink>; Berlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Institut für Biologie, Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.<br /><searchLink fieldCode="AU" term="%22Nishanth+G%22">Nishanth G</searchLink>; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schlüter+D%22">Schlüter D</searchLink>; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de.; Cluster of Excellence-Resolving Infection Susceptibility (RESIST), (EXC 2155), Hannover Medical School, Hannover, Germany. Schlueter.dirk@mh-hannover.de.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 20; Vol. 16 (1), pp. 9279. <i>Date of Electronic Publication: </i>2025 Oct 20.
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