Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator.

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Title: Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator.
Authors: Haile MT; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Shukla A; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA., Zhen J; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Mather MW; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA., Bhatnagar S; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA., Morrisey JM; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA., Zhang Z; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Vaidya AB; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA. av27@drexel.edu., Ho CM; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. chi-min.ho@columbia.edu.
Source: Nature communications [Nat Commun] 2025 Oct 20; Vol. 16 (1), pp. 9092. Date of Electronic Publication: 2025 Oct 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-64815-y