Acidic melanoma microenvironment selects for a senescence-like but also migratory-active subpopulation driving metastatic disease.

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Title: Acidic melanoma microenvironment selects for a senescence-like but also migratory-active subpopulation driving metastatic disease.
Authors: Chiheb C; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Fischer S; Faculty of Computer Science, Deggendorf Institute of Technology, Deggendorf, Germany., El Ahmad Z; Faculty of Computer Science, Deggendorf Institute of Technology, Deggendorf, Germany., Henz I; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Böhme-Schäfer I; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Department Hamm 2, Hochschule Hamm-Lippstadt, Hamm, Germany., Kappelmann-Fenzl M; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Faculty of Computer Science, Deggendorf Institute of Technology, Deggendorf, Germany., Bosserhoff AK; Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. anja.bosserhoff@fau.de.; CCC WERA: Comprehensive Cancer Center Alliance WERA (CCC WERA), Erlangen, Germany. anja.bosserhoff@fau.de.; BZKF: Bavarian Cancer Research Center (BZKF), Erlangen, Germany. anja.bosserhoff@fau.de.
Source: Cell death discovery [Cell Death Discov] 2025 Oct 20; Vol. 11 (1), pp. 469. Date of Electronic Publication: 2025 Oct 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2058-7716
DOI:10.1038/s41420-025-02806-0