Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration.

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Title: Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration.
Authors: Gamen E; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Price EL; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Pezzolla D; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., De Villiers C; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Gunadasa-Rohling M; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Lokman AB; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Cosma MA; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Sayers J; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Silva CR; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Salama R; NDM Research Building, University of Oxford, Oxford, United Kingdom., Mole DR; NDM Research Building, University of Oxford, Oxford, United Kingdom., Bishop T; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.; NDM Research Building, University of Oxford, Oxford, United Kingdom.; Ludwig institute for Cancer Research, University of Oxford, Oxford, United Kingdom., Pugh CW; Target Discovery Institute, University of Oxford, Oxford, United Kingdom., Choudhury RP; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Carr CA; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., Vieira JM; School of Cardiovascular and Metabolic Medicine and Sciences, British Heart Foundation Centre of Research Excellence, King's College London, London, United Kingdom., Riley PR; Institute of Developmental and Regenerative Medicine (IDRM), Oxford, United Kingdom.; Burdon-Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Source: ELife [Elife] 2025 Oct 22; Vol. 14. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.107419