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Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer.

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Title: Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer.
Authors: Chan Wah Hak C; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Patin EC; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Patrikeev A; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Nicastri A; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom., Kozik Z; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom., Baldock H; Biological Services Unit, The Institute of Cancer Research, London, United Kingdom., Kyula-Currie JN; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Roulstone V; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Wongariyapak A; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Gifford V; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom., Tenev T; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom., Appleton ES; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Hubbard LC; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Foo S; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Pedersen M; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Choudhary JS; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom., Ono M; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom., Melcher AA; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Rullan A; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom., Harrington KJ; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.
Source: Cancer research communications [Cancer Res Commun] 2025 Nov 01; Vol. 5 (11), pp. 2079-2091.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chan+Wah+Hak+C%22">Chan Wah Hak C</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Patin+EC%22">Patin EC</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Patrikeev+A%22">Patrikeev A</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nicastri+A%22">Nicastri A</searchLink>; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kozik+Z%22">Kozik Z</searchLink>; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Baldock+H%22">Baldock H</searchLink>; Biological Services Unit, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kyula-Currie+JN%22">Kyula-Currie JN</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Roulstone+V%22">Roulstone V</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wongariyapak+A%22">Wongariyapak A</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gifford+V%22">Gifford V</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tenev+T%22">Tenev T</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Appleton+ES%22">Appleton ES</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hubbard+LC%22">Hubbard LC</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Foo+S%22">Foo S</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pedersen+M%22">Pedersen M</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Choudhary+JS%22">Choudhary JS</searchLink>; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ono+M%22">Ono M</searchLink>; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Melcher+AA%22">Melcher AA</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rullan+A%22">Rullan A</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harrington+KJ%22">Harrington KJ</searchLink>; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom.
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