Structural mechanism of the agonist binding on human TRPC3 channel.
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| Title: | Structural mechanism of the agonist binding on human TRPC3 channel. |
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| Authors: | Chen Y; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China., Zang J; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Guo W; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China., Xu J; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Wei M; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Quan L; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Zhu M; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China., Zhao X; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China., Peng H; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China., Wan Y; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China., Chen L; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China. chenlei2016@pku.edu.cn.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; National Biomedical Imaging Center, Peking University, Beijing, China. chenlei2016@pku.edu.cn. |
| Source: | Nature communications [Nat Commun] 2025 Oct 22; Vol. 16 (1), pp. 9343. Date of Electronic Publication: 2025 Oct 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64435-6 |
