Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes.
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| Title: | Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes. |
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| Authors: | DeMeo B; Cellarity Inc, Somerville, MA, USA., Nesbitt C; Cellarity Inc, Somerville, MA, USA., Miller SA; Cellarity Inc, Somerville, MA, USA., Burkhardt DB; Cellarity Inc, Somerville, MA, USA., Lipchina I; Cellarity Inc, Somerville, MA, USA., Fu D; Cellarity Inc, Somerville, MA, USA., Holderrieth P; Cellarity Inc, Somerville, MA, USA., Kim D; Cellarity Inc, Somerville, MA, USA., Kolchenko S; Cellarity Inc, Somerville, MA, USA., Szalata A; Computational Health Center, Institute of Computational Biology, Helmholtz-Munich, Neuherberg, Germany.; TUM School of Computation, Information and Technology, Technical University of Munich, Garching, Germany., Gupta I; Cellarity Inc, Somerville, MA, USA., Kerr C; Cellarity Inc, Somerville, MA, USA., Pfefer T; Cellarity Inc, Somerville, MA, USA., Rojas-Rodriguez R; Cellarity Inc, Somerville, MA, USA., Kuppassani S; Cellarity Inc, Somerville, MA, USA., Kruidenier L; Cellarity Inc, Somerville, MA, USA., Doshi PB; Cellarity Inc, Somerville, MA, USA., Zamanighomi M; Cellarity Inc, Somerville, MA, USA., Collins JJ; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, MIT Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wyss Institute, Harvard University, Boston, MA, USA., Shalek AK; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Chemistry and Koch Institute for Integrative Cancer Research, MIT Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA., Theis FJ; Computational Health Center, Institute of Computational Biology, Helmholtz-Munich, Neuherberg, Germany.; TUM School of Computation, Information and Technology, Technical University of Munich, Garching, Germany.; Helmholtz AI, Helmholtz-Munich, Neuherberg, Germany., Cortes M; Cellarity Inc, Somerville, MA, USA. |
| Source: | Science (New York, N.Y.) [Science] 2025 Nov 27; Vol. 390 (6776), pp. eadi8577. Date of Electronic Publication: 2025 Nov 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adi8577 |
