High mesothelin expression is associated with low cytotoxic T cell infiltration in pancreatic cancer.

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Title: High mesothelin expression is associated with low cytotoxic T cell infiltration in pancreatic cancer.
Authors: Liang O; Precision Oncology Laboratory, Cancer Innovations, Centenary Institute, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., White AL; Precision Oncology Laboratory, Cancer Innovations, Centenary Institute, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Fielder T; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Sydney, NSW, Australia., Shin JS; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Sydney, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Sagnella SM; Precision Oncology Laboratory, Cancer Innovations, Centenary Institute, Sydney, NSW, Australia.; Cell and Molecular Therapies, Royal Prince Alfred Hospital, Sydney Local Health District, Sydney, NSW, Australia., Schmitz U; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Computational Biomedicine Lab, College of Science and Engineering, James Cook University, Townsville, QLD, Australia., Yeo D; Precision Oncology Laboratory, Cancer Innovations, Centenary Institute, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Cell and Molecular Therapies, Royal Prince Alfred Hospital, Sydney Local Health District, Sydney, NSW, Australia.
Source: Frontiers in immunology [Front Immunol] 2025 Oct 08; Vol. 16, pp. 1651687. Date of Electronic Publication: 2025 Oct 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1651687