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Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism.

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Title: Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism.
Authors: Dufau J; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Recazens E; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Bottin L; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Bergoglio C; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Mairal A; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Chaoui K; IPBS, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Toulouse, France., Marques MA; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Jimenez V; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain., García M; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain., Wang T; Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland., Laurell H; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Iacovoni JS; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Flores-Flores R; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Denechaud PD; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Acheikh Ibn Oumar K; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Amri EZ; iBV, Université Côte d'Azur, CNRS, Inserm, Adipo-Cible Research Study Group, Nice, France., Postic C; Institut Cochin, Université de Paris, CNRS, Inserm, Paris, France., Concordet JP; Museum National d'Histoire Naturelle, Inserm, CNRS, Laboratoire Structure et Instabilité des Génomes, Paris, France., Gourdy P; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Mejhert N; Department of Medicine (H7), Karolinska Institutet, and Karolinska University Hospital, ME Endokrinologi, Stockholm, Sweden., Rydén M; Department of Medicine (H7), Karolinska Institutet, and Karolinska University Hospital, ME Endokrinologi, Stockholm, Sweden., Burlet-Schiltz O; IPBS, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Toulouse, France., Bosch F; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain., Wolfrum C; Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland., Mouisel E; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France., Tavernier G; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; CREFRE-ANEXPLO, Université de Toulouse, Inserm, Ecole Nationale Vétérinaire de Toulouse, Toulouse, France., Langin D; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; Centre Hospitalier Universitaire de Toulouse, Toulouse, France; IUF, Institut Universitaire de France, Paris, France. Electronic address: dominique.langin@inserm.fr.
Source: Cell metabolism [Cell Metab] 2025 Nov 04; Vol. 37 (11), pp. 2250-2263.e9. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
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  Data: Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Dufau+J%22">Dufau J</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Recazens+E%22">Recazens E</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bottin+L%22">Bottin L</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bergoglio+C%22">Bergoglio C</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Mairal+A%22">Mairal A</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Chaoui+K%22">Chaoui K</searchLink>; IPBS, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Marques+MA%22">Marques MA</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Jimenez+V%22">Jimenez V</searchLink>; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García+M%22">García M</searchLink>; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland.<br /><searchLink fieldCode="AU" term="%22Laurell+H%22">Laurell H</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Iacovoni+JS%22">Iacovoni JS</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Flores-Flores+R%22">Flores-Flores R</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Denechaud+PD%22">Denechaud PD</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Acheikh+Ibn+Oumar+K%22">Acheikh Ibn Oumar K</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Amri+EZ%22">Amri EZ</searchLink>; iBV, Université Côte d'Azur, CNRS, Inserm, Adipo-Cible Research Study Group, Nice, France.<br /><searchLink fieldCode="AU" term="%22Postic+C%22">Postic C</searchLink>; Institut Cochin, Université de Paris, CNRS, Inserm, Paris, France.<br /><searchLink fieldCode="AU" term="%22Concordet+JP%22">Concordet JP</searchLink>; Museum National d'Histoire Naturelle, Inserm, CNRS, Laboratoire Structure et Instabilité des Génomes, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gourdy+P%22">Gourdy P</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; Centre Hospitalier Universitaire de Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Mejhert+N%22">Mejhert N</searchLink>; Department of Medicine (H7), Karolinska Institutet, and Karolinska University Hospital, ME Endokrinologi, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Rydén+M%22">Rydén M</searchLink>; Department of Medicine (H7), Karolinska Institutet, and Karolinska University Hospital, ME Endokrinologi, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Burlet-Schiltz+O%22">Burlet-Schiltz O</searchLink>; IPBS, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bosch+F%22">Bosch F</searchLink>; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Wolfrum+C%22">Wolfrum C</searchLink>; Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mouisel+E%22">Mouisel E</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Tavernier+G%22">Tavernier G</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; CREFRE-ANEXPLO, Université de Toulouse, Inserm, Ecole Nationale Vétérinaire de Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Langin+D%22">Langin D</searchLink>; I2MC, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Toulouse, France; Centre Hospitalier Universitaire de Toulouse, Toulouse, France; IUF, Institut Universitaire de France, Paris, France. Electronic address: dominique.langin@inserm.fr.
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  Data: <searchLink fieldCode="JN" term="%22101233170%22">Cell metabolism</searchLink> [Cell Metab] 2025 Nov 04; Vol. 37 (11), pp. 2250-2263.e9. <i>Date of Electronic Publication: </i>2025 Oct 23.
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