Development of [18F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology.
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| Title: | Development of [18F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology. |
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| Authors: | Vokali E; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Chevalier E; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Dreyfus N; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Charmey D; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Melly T; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Kocher J; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Ratnam M; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Serra AM; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Jaquier T; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Delgado C; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Ravache M; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Scialò C; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Cappelli S; Molecular Pathology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy., Kroth H; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Capotosti F; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Luthi-Carter R; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Afroz T; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Derouazi M; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Constantinescu CC; Perceptive Inc., New Haven, CT, USA., Seelaar H; Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands., Buratti E; Molecular Pathology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy., Nelson PT; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Polymenidou M; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Pfeifer A; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Kosco-Vilbois M; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland., Seredenina T; AC Immune SA, EPFL Innovation Park, Building B, Lausanne, Switzerland. tamara.seredenina@acimmune.com. |
| Source: | Nature communications [Nat Commun] 2025 Oct 24; Vol. 16 (1), pp. 9358. Date of Electronic Publication: 2025 Oct 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64540-6 |
