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Tissue microenvironment dictates the state of human iPSC-derived endothelial cells of distinct developmental origin in 3D cardiac microtissues.

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Title: Tissue microenvironment dictates the state of human iPSC-derived endothelial cells of distinct developmental origin in 3D cardiac microtissues.
Authors: Cao X; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Mircea M; Leiden Institute of Physics, Leiden University, RA 2333, Leiden, the Netherlands., Cascione S; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Amel A; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Tsikari T; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., van den Hil FE; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Mei H; Sequencing Analysis Support Core, Leiden University Medical Center, Leiden 2333ZA, the Netherlands., Neumann K; Stem Cell Engineering, Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden 01307, Germany., Alemany A; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Anastassiadis K; Stem Cell Engineering, Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden 01307, Germany., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands., Semrau S; Leiden Institute of Physics, Leiden University, RA 2333, Leiden, the Netherlands., Orlova VV; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.
Source: IScience [iScience] 2025 Sep 22; Vol. 28 (10), pp. 113611. Date of Electronic Publication: 2025 Sep 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cao+X%22">Cao X</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mircea+M%22">Mircea M</searchLink>; Leiden Institute of Physics, Leiden University, RA 2333, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cascione+S%22">Cascione S</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Amel+A%22">Amel A</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Tsikari+T%22">Tsikari T</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Hil+FE%22">van den Hil FE</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mei+H%22">Mei H</searchLink>; Sequencing Analysis Support Core, Leiden University Medical Center, Leiden 2333ZA, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Neumann+K%22">Neumann K</searchLink>; Stem Cell Engineering, Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Alemany+A%22">Alemany A</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Anastassiadis+K%22">Anastassiadis K</searchLink>; Stem Cell Engineering, Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Mummery+CL%22">Mummery CL</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Semrau+S%22">Semrau S</searchLink>; Leiden Institute of Physics, Leiden University, RA 2333, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Orlova+VV%22">Orlova VV</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333ZC, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2025 Sep 22; Vol. 28 (10), pp. 113611. <i>Date of Electronic Publication: </i>2025 Sep 22 (<i>Print Publication: </i>2025).
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