Inflammasome targeting for periodontitis prevention is sex dependent.

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Bibliographic Details
Title: Inflammasome targeting for periodontitis prevention is sex dependent.
Authors: Alves T; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Swanson KV; Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC 27599.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599., Girnary MS; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Freire M; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA 92093.; Department of Genomic Medicine and Infectious Diseases, J. Craig Venter Institute, La Jolla, CA 92037., Moss K; Department of Biostatistics and Health Data Science, School of Medicine, University of Indiana, Indianapolis, IN 46202., Divaris K; Department of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Beck J; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Santos PCP; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Brickey WJ; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599., Wrobel JA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599.; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599., Min HY; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Syed M; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Morelli T; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Seaman WT; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892., Preisser JS; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599., Hu D; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599., Preisser H; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Makhanova N; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Susin C; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Vias NP; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Styner M; Division of Endocrinology and Metabolism, School of Medicine, University of North Carolina, Chapel Hill, NC 27599., Zhang S; Periodontics Department, College of Dentistry, University of Iowa, Iowa City, IA 52242., Pirih FQ; Division of Regenerative and Reconstructive Sciences, School of Dentistry, University of California Los Angeles, Los Angeles, CA 90095., Chang J; Division of Regenerative and Reconstructive Sciences, School of Dentistry, University of California Los Angeles, Los Angeles, CA 90095., Gill HS; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695., Lietzan AD; Department of Biomedical Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599., Webster-Cyriaque J; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892., Ting JPY; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599.; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599., Marchesan JT; Department of Periodontology, Endodontics, and Dental Hygiene, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 04; Vol. 122 (44), pp. e2507092122. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2507092122