The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial.

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Title: The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial.
Authors: Burgess J; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, St. Nicholas Hospital, Jubilee Road, Gosforth, Newcastle upon Tyne, Tyne and Wear, NE3 3XT, UK.; Newcastle University, Newcastle-Upon-Tyne, NE1 7RU, UK., Ismail K; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK. khalida.2.ismail@kcl.ac.uk., Raymont V; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK., Emsley R; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK., Beckley-Hoelscher N; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK., Wall J; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK., Dilley M; King's College Hospital, Denmark Hill, London, SE5 9RS, UK., Ahmed AI; King's College Hospital, Denmark Hill, London, SE5 9RS, UK., Barrett B; Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience King's College London, SE5 8AF, London, UK., Longson D; Manchester Academic Health Science Centre, Manchester Mental Health NHS Foundation Trust, Manchester, Greater, UK.
Corporate Authors: STOP-D Trial Group
Source: Trials [Trials] 2025 Oct 27; Vol. 26 (1), pp. 438. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1745-6215
DOI:10.1186/s13063-025-09027-x