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The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial.

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Title: The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial.
Authors: Burgess J; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, St. Nicholas Hospital, Jubilee Road, Gosforth, Newcastle upon Tyne, Tyne and Wear, NE3 3XT, UK.; Newcastle University, Newcastle-Upon-Tyne, NE1 7RU, UK., Ismail K; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK. khalida.2.ismail@kcl.ac.uk., Raymont V; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK., Emsley R; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK., Beckley-Hoelscher N; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK., Wall J; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK., Dilley M; King's College Hospital, Denmark Hill, London, SE5 9RS, UK., Ahmed AI; King's College Hospital, Denmark Hill, London, SE5 9RS, UK., Barrett B; Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience King's College London, SE5 8AF, London, UK., Longson D; Manchester Academic Health Science Centre, Manchester Mental Health NHS Foundation Trust, Manchester, Greater, UK.
Corporate Authors: STOP-D Trial Group
Source: Trials [Trials] 2025 Oct 27; Vol. 26 (1), pp. 438. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Burgess+J%22">Burgess J</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, St. Nicholas Hospital, Jubilee Road, Gosforth, Newcastle upon Tyne, Tyne and Wear, NE3 3XT, UK.; Newcastle University, Newcastle-Upon-Tyne, NE1 7RU, UK.<br /><searchLink fieldCode="AU" term="%22Ismail+K%22">Ismail K</searchLink>; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK. khalida.2.ismail@kcl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Raymont+V%22">Raymont V</searchLink>; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK.<br /><searchLink fieldCode="AU" term="%22Emsley+R%22">Emsley R</searchLink>; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK.<br /><searchLink fieldCode="AU" term="%22Beckley-Hoelscher+N%22">Beckley-Hoelscher N</searchLink>; Department of Biostatistics and Health Informatics, Institute of Psychiatry, King's College London, Psychology & Neuroscience16 De Crespigny Park, London, SE5 8AF, UK.<br /><searchLink fieldCode="AU" term="%22Wall+J%22">Wall J</searchLink>; Department of Psychological Medicine, King's College London, Weston Education Centre10 Cutcombe Road, London, SE5 9RJ, UK.<br /><searchLink fieldCode="AU" term="%22Dilley+M%22">Dilley M</searchLink>; King's College Hospital, Denmark Hill, London, SE5 9RS, UK.<br /><searchLink fieldCode="AU" term="%22Ahmed+AI%22">Ahmed AI</searchLink>; King's College Hospital, Denmark Hill, London, SE5 9RS, UK.<br /><searchLink fieldCode="AU" term="%22Barrett+B%22">Barrett B</searchLink>; Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience King's College London, SE5 8AF, London, UK.<br /><searchLink fieldCode="AU" term="%22Longson+D%22">Longson D</searchLink>; Manchester Academic Health Science Centre, Manchester Mental Health NHS Foundation Trust, Manchester, Greater, UK.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2025 Oct 27; Vol. 26 (1), pp. 438. <i>Date of Electronic Publication: </i>2025 Oct 27.
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              Text: 2025 Oct 27
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