Intestine-derived sorbitol drives steatotic liver disease in the absence of gut bacteria.
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| Title: | Intestine-derived sorbitol drives steatotic liver disease in the absence of gut bacteria. |
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| Authors: | Jackstadt MM; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Fowle-Grider R; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Song MG; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Ward MH; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Barr M; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Cho K; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Palacios HH; Center for Human Nutrition, Washington University in St. Louis, St. Louis, MO 63110, USA., Klein S; Center for Human Nutrition, Washington University in St. Louis, St. Louis, MO 63110, USA., Shriver LP; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA., Patti GJ; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO 63130, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA. |
| Source: | Science signaling [Sci Signal] 2025 Oct 28; Vol. 18 (910), pp. eadt3549. Date of Electronic Publication: 2025 Oct 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adt3549 |
