Plasmid dynamics driving carbapenemase gene dissemination in healthcare environments: a nationwide analysis of closed Enterobacterales genomes.
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| Title: | Plasmid dynamics driving carbapenemase gene dissemination in healthcare environments: a nationwide analysis of closed Enterobacterales genomes. |
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| Authors: | Koh V; NCID Research Office, National Centre for Infectious Diseases, Singapore, Singapore., Cabrera R; School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá, Colombia., Sridatta PSR; NCID Research Office, National Centre for Infectious Diseases, Singapore, Singapore., Thevasagayam NM; NCID Research Office, National Centre for Infectious Diseases, Singapore, Singapore., Lim ZQ; NCID Research Office, National Centre for Infectious Diseases, Singapore, Singapore., Marimuthu K; Department of Infectious Diseases, National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Venkatachalam I; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Cherng BPZ; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.; DUKE-NUS Graduate Medical School, National University of Singapore, Singapore, Singapore., Fong RKC; Department of Infectious Diseases, Changi General Hospital, Singapore, Singapore., Pada SK; Department of Infectious Diseases, Ng Teng Fong General Hospital, Singapore, Singapore., Ooi ST; Division of Infectious Diseases, Department of General Medicine, Khoo Teck Puat Hospital, Singapore, Singapore., Smitasin N; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Division of Infectious Diseases, National University Hospital and National University Health System, Singapore, Singapore., Thoon KC; Infectious Diseases Service, KK Women's and Children's Hospital, Singapore, Singapore., Hsu LY; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Singapore Centre for Environmental Life Sciences Engineering, National University of, Singapore, Singapore., Koh TH; Department of Microbiology, Singapore General Hospital, Singapore, Singapore., De PP; Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore., Tan TY; Department of Laboratory Medicine, Changi General Hospital, Singapore, Singapore., Chan D; Department of Laboratory Medicine, Ng Teng Fong General Hospital, Singapore, Singapore., Deepak RN; Department of Laboratory Medicine, Khoo Teck Puat Hospital, Singapore, Singapore., Tee NWS; Department of Laboratory Medicine, National University Hospital and National University Health System, Singapore, Singapore., Gan YH; Infectious Diseases Translational Research Program, Department of Biochemistry, National University of, Singapore, Singapore., Matlock W; Department of Biology, University of Oxford, Oxford, United Kingdom., Eyre DW; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Ang M; National Public Health Laboratory, National Centre for Infectious Diseases, Singapore, Singapore., Lin RTP; Department of Laboratory Medicine, National University Hospital and National University Health System, Singapore, Singapore.; National Public Health Laboratory, National Centre for Infectious Diseases, Singapore, Singapore., Teo J; Department of Laboratory Medicine, National University Hospital and National University Health System, Singapore, Singapore., Ng OT; Department of Infectious Diseases, National Centre for Infectious Diseases, Singapore, Singapore. oon.tek.ng@nhghealth.com.sg.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore. oon.tek.ng@nhghealth.com.sg.; Infectious Disease Research Laboratory, National Centre for Infectious Diseases, Singapore, Singapore. oon.tek.ng@nhghealth.com.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. oon.tek.ng@nhghealth.com.sg. |
| Corporate Authors: | Carbapenemase-Producing Enterobacteriaceae in Singapore (CaPES) Study Group |
| Source: | Nature communications [Nat Commun] 2025 Oct 28; Vol. 16 (1), pp. 9522. Date of Electronic Publication: 2025 Oct 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64515-7 |