The Esc(1-21)-1c Antimicrobial Peptide Inhibits a Specific Transcriptional Activator of the MexAB-OprM Efflux Pump in P. aeruginosa.

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Title: The Esc(1-21)-1c Antimicrobial Peptide Inhibits a Specific Transcriptional Activator of the MexAB-OprM Efflux Pump in P. aeruginosa.
Authors: Canè C; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', 80131 Naples, Italy., Casciaro B; Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy., Vetrano C; Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy., Tammaro L; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Department of Chemical Sciences, University of Naples 'Federico II', 80126 Naples, Italy., Platella C; Department of Chemical Sciences, University of Naples 'Federico II', 80126 Naples, Italy., Musumeci D; Department of Chemical Sciences, University of Naples 'Federico II', 80126 Naples, Italy.; Institute of Biostructure and Bioimaging (IBB)-CNR, 80145 Naples, Italy., Mangoni ML; Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy., Duilio A; Department of Chemical Sciences, University of Naples 'Federico II', 80126 Naples, Italy.; National Institute of Biostructure and Biosystems (INBB), 00165 Rome, Italy., Di Somma A; Department of Chemical Sciences, University of Naples 'Federico II', 80126 Naples, Italy.
Source: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 13; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms26209940