A novel TIRAP-MyD88 inhibitor blocks TLR7- and TLR8-induced type I IFN responses.

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Bibliographic Details
Title: A novel TIRAP-MyD88 inhibitor blocks TLR7- and TLR8-induced type I IFN responses.
Authors: Nilsen KE; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Stenvik J; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Skjesol A; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Mestvedt IB; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Bakke SS; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Giambelluca MS; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Gravastrand CS; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Elamurugan K; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Ryan L; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Espevik T; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Infectious Diseases, Clinic of Medicine, St. Olavs Hospital HF, Trondheim University Hospital, Trondheim, Norway., Yurchenko M; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Infectious Diseases, Clinic of Medicine, St. Olavs Hospital HF, Trondheim University Hospital, Trondheim, Norway.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2025 Dec 01; Vol. 214 (12), pp. 3514-3528.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1550-6606
DOI:10.1093/jimmun/vkaf258