Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy.
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| Title: | Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy. |
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| Authors: | Fonseca MM; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Gelblung O; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Pennypacker SD; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Brooks T; Section on Hematology and Oncology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Cancer Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Limia M; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Morgan JW; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Zhu X; Section on Molecular Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Tovias-Sanchez LC; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Pluma-Pluma A; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Martinez RE; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Eber MR; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Park SH; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Furdui CM; Section on Molecular Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Awasthi D; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Emmanuelli A; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.; Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Cho BA; Precision Immunology Institute, Hess Center for Science and Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Tan C; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Shalowitz DI; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; West Michigan Cancer Center, Kalamazoo, MI 49007, USA., Lentz SS; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Kelly M; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., O'Brien Cox A; Proteomics and Metabolomics Shared Resource, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Macnamara L; Proteomics and Metabolomics Shared Resource, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Hsu FC; Division of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Shiozawa Y; Department of Cancer Biology and Wake Forest Baptist Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Hsu W; Department of Neurosurgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Iwawaki T; Division of Cell Medicine, Medical Research Institute, Kanazawa Medical University, Ishikawa, Japan., Miller LD; Department of Cancer Biology and Wake Forest Baptist Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Lesser GJ; Department of Cancer Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Strowd R; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Cubillos-Ruiz JR; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.; Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Romero-Sandoval EA; Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2025 Oct 29; Vol. 17 (822), pp. eady5288. Date of Electronic Publication: 2025 Oct 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.ady5288 |
