Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration.
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| Title: | Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration. |
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| Authors: | Gao S; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Su NN; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Zhao Q; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Wang FF; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Wang SC; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Guo W; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; Hebei Key Laboratory of Integrated Traditional and Western Medicine in Osteoarthrosis Research, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; The Hebei Province Integrated Traditional Chinese and Western Medicine 3D Printing Technology Innovation Center, Cangzhou, 061001, People's Republic of China. guow0319@163.com. |
| Source: | Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Oct 29; Vol. 20 (1), pp. 934. Date of Electronic Publication: 2025 Oct 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1749-799X |
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| DOI: | 10.1186/s13018-025-06382-y |