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Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration.

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Title: Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration.
Authors: Gao S; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Su NN; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Zhao Q; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Wang FF; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Wang SC; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China., Guo W; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; Hebei Key Laboratory of Integrated Traditional and Western Medicine in Osteoarthrosis Research, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; The Hebei Province Integrated Traditional Chinese and Western Medicine 3D Printing Technology Innovation Center, Cangzhou, 061001, People's Republic of China. guow0319@163.com.
Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Oct 29; Vol. 20 (1), pp. 934. Date of Electronic Publication: 2025 Oct 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Su+NN%22">Su NN</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+Q%22">Zhao Q</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+FF%22">Wang FF</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+SC%22">Wang SC</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Guo+W%22">Guo W</searchLink>; Department of Orthopaedics, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine, 31 Huanghe road, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; Hebei Key Laboratory of Integrated Traditional and Western Medicine in Osteoarthrosis Research, Cangzhou, 061001, People's Republic of China. guow0319@163.com.; The Hebei Province Integrated Traditional Chinese and Western Medicine 3D Printing Technology Innovation Center, Cangzhou, 061001, People's Republic of China. guow0319@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101265112%22">Journal of orthopaedic surgery and research</searchLink> [J Orthop Surg Res] 2025 Oct 29; Vol. 20 (1), pp. 934. <i>Date of Electronic Publication: </i>2025 Oct 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265112 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1749-799X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221749799X%22">1749799X </searchLink><i>NLM ISO Abbreviation: </i>J Orthop Surg Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13018-025-06382-y
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      – Code: eng
        Text: English
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      – TitleFull: Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration.
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            NameFull: Gao S
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            – D: 29
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              Text: 2025 Oct 29
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              Y: 2025
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