Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.
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| Title: | Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions. |
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| Authors: | Tian DD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Hall SD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Chapman SC; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Posada MM; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA. |
| Source: | CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2025 Dec; Vol. 14 (12), pp. 2221-2231. Date of Electronic Publication: 2025 Oct 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2163-8306 |
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| DOI: | 10.1002/psp4.70134 |