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Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.

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Title: Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.
Authors: Tian DD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Hall SD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Chapman SC; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Posada MM; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA.
Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2025 Dec; Vol. 14 (12), pp. 2221-2231. Date of Electronic Publication: 2025 Oct 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.
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  Data: <searchLink fieldCode="AU" term="%22Tian+DD%22">Tian DD</searchLink>; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Hall+SD%22">Hall SD</searchLink>; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+SC%22">Chapman SC</searchLink>; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Posada+MM%22">Posada MM</searchLink>; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101580011 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2163-8306 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221638306%22">21638306 </searchLink><i>NLM ISO Abbreviation: </i>CPT Pharmacometrics Syst Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1002/psp4.70134
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      – Code: eng
        Text: English
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        StartPage: 2221
    Titles:
      – TitleFull: Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.
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            NameFull: Tian DD
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            NameFull: Hall SD
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            NameFull: Chapman SC
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            – D: 01
              M: 12
              Text: 2025 Dec
              Type: published
              Y: 2025
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              Value: 14
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