Childhood gut microbiome is linked to internalizing symptoms at school age via the functional connectome.
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| Title: | Childhood gut microbiome is linked to internalizing symptoms at school age via the functional connectome. |
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| Authors: | Querdasi FR; Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA. frq@ucla.edu., Uy JP; Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychology, Stanford University, Stanford, CA, USA., Labus JS; Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, CA, USA.; G. Oppenheimer Center for Neurobiology of Stress and Resilience, Los Angeles, CA, USA.; Goodman-Luskin Microbiome Center, University of California, Los Angeles, CA, USA.; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Xu J; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Karnani N; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Tan AP; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Broekman BBFP; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Gluckman PD; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore.; Liggins Institute, University of Auckland, Auckland, New Zealand., Chong YS; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore.; Department of Obstetrics and Gynaecology, National University Health System, Singapore City, Singapore., Chen H; Psychiatry and Radiology, KK Women's and Children's Hospital, Singapore City, Singapore., Fortier MV; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Daniel LM; Duke-National University of Singapore Medical School, Singapore City, Singapore.; Department of Child Development, KK Women's and Children's Hospital, Singapore City, Singapore., Yap F; Department of Paediatrics, KK Women's and Children's Hospital, Singapore City, Singapore.; Department of Pediatrics, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore City, Singapore.; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore City, Singapore., Eriksson JG; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo School of Medicine, National University of Singapore, Singapore City, Singapore.; Department of General Practice and Primary Health, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Program of Public Health Research, Folkhälsan Research Center, Helsinki, Finland., Cai S; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Chong MF; Saw Swee Hock School of Public Health, National University of Singapore, Singapore City, Singapore., Toh JY; Institute for Human Development and Potential, Agency for Science, Technology and Research in Singapore, Singapore City, Singapore., Godfrey KM; Medical Research Council Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK., Meaney MJ; Department of Psychiatry, Douglas Hospital Research Centre, McGill University, Montreal, QC, Canada.; Brain-Body Initiative, Agency for Science, Technology and Research, Singapore City, Singapore., Callaghan BL; Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA. |
| Source: | Nature communications [Nat Commun] 2025 Oct 30; Vol. 16 (1), pp. 9359. Date of Electronic Publication: 2025 Oct 30. |
| Publication Type: | Journal Article; Observational Study |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64988-6 |