Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ.

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Title: Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ.
Authors: Sveidahl Johansen O; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark., McIntyre RL; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark; Center for Adipocyte Signaling, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark., Rahbani JF; Section of Hematology and Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Zhang Q; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada., Scholtes C; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada; Laboratoire CarMeN, UMR INSERM U1060/INRA U1397, Université Claude Bernard Lyon 1, F-69310 Pierre-Bénite and F-69500 Bron, France., Lagarde DM; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada., Billon C; Department of Pharmaceutical and Administrative Sciences, Center for Clinical Pharmacology, Washington University School of Medicine and St. Louis College of Pharmacy, St. Louis, MO 63110, USA., Côté I; Department of Cellular and Systems Pharmacology, University of Florida College of Pharmacy and University of Florida Genetics Institute, Gainesville, FL 32610, USA., Delgado-Martin M; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada., Tandio D; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark., Basse AL; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark; Center for Adipocyte Signaling, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark., Eury E; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Kralli A; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Burris TP; Department of Cellular and Systems Pharmacology, University of Florida College of Pharmacy and University of Florida Genetics Institute, Gainesville, FL 32610, USA., Giguère V; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada., Kazak L; Rosalind & Morris Goodman Cancer Institute and Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada., Gerhart-Hines Z; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark; Center for Adipocyte Signaling, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark; Embark Laboratories ApS, Ottiliavej 9, 2500 Valby, Denmark; Incipiam Pharma ApS, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark. Electronic address: zpg@sund.ku.dk.
Source: Molecular metabolism [Mol Metab] 2026 Jan; Vol. 103, pp. 102277. Date of Electronic Publication: 2025 Oct 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2212-8778
DOI:10.1016/j.molmet.2025.102277