Gut bacterial dysbiosis in pediatric severe malaria associates with post-discharge mortality.

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Title: Gut bacterial dysbiosis in pediatric severe malaria associates with post-discharge mortality.
Authors: Bednarski OJ; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA., Lehman SB; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Mzinza D; Department of Biological Sciences, Academy of Medical Sciences, Malawi University of Science and Technology, Limbe, Malawi.; Center for Clinical and Biological Sciences Research (CCBSR), Academy of Medical Sciences, Malawi University of Science and Technology, Thyolo, Malawi.; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Kazinga C; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda., Namazzi R; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.; Global Health Uganda, Kampala, Uganda., Opoka RO; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.; Global Health Uganda, Kampala, Uganda.; Aga Khan University East Africa Medical College, Nairobi, Kenya., Ren J; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA., Tran TM; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.; Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Taylor TE; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.; College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA., Seydel KB; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.; College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA., John CC; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Conroy AL; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Schmidt NW; Ryan White Center for Pediatric Infectious Diseases and Global Health, Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA. nwschmid@iu.edu.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA. nwschmid@iu.edu.
Source: Nature communications [Nat Commun] 2025 Oct 31; Vol. 16 (1), pp. 9658. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-64632-3