Opportunities and Challenges With CAR T-cell Treatment of Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia: Review and Recommendations From the Westhafen Intercontinental Group.

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Title: Opportunities and Challenges With CAR T-cell Treatment of Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia: Review and Recommendations From the Westhafen Intercontinental Group.
Authors: Deimundo Roura C; Division of Pediatric Hematology and Oncology, Intermountain Primary Children's Hospital, Huntsman Cancer Institute, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah., Amrolia P; Department of Bone Marrow Transplant, Great Ormond St Children's Hospital, London, United Kingdom., Ansari M; Cansearch Research platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland., Bader P; Department of Pediatrics, Division for Stem Cell Transplantation and Immunology, Goethe University Frankfurt, Frankfurt a. Main, Germany., Balduzzi A; Department of Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy., Buechner J; Oslo University Hospital, Department of Pediatric Hematology and Oncology, Oslo, Norway., Hsieh EM; Division of Hematology/Oncology/Transplantation and Cellular Therapy, Children's Hospital Los Angeles Cancer and Blood Disease Institute, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California., Myers RM; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Ottaviano G; Department of Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Peters C; St. Anna Children's Hospital, Medical University of Vienna, St. Anna Children's Cancer Research Institute, Vienna, Austria., Rouce RH; Center for Cell and Gene Therapy, Dan L. Duncan Comprehensive Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Shah NN; Pediatric Oncology Branch, National Cancer Institute/Center for Cancer Research, National Institutes of Health, Bethesda, Maryland., Verneris MR; Department of Pediatric Hematology, Oncology, BMT, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Kalwak K; Department of Pediatric Hematology, Oncology and BMT, Wroclaw Medical University, Wroclaw, Poland and EBMT Pediatric Diseases Working Party, Paris, France., Pulsipher MA; Division of Pediatric Hematology and Oncology, Intermountain Primary Children's Hospital, Huntsman Cancer Institute, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah. Electronic address: michael.pulsipher@hci.utah.edu.
Source: Transplantation and cellular therapy [Transplant Cell Ther] 2026 Mar; Vol. 32 (3), pp. 261-276. Date of Electronic Publication: 2025 Oct 30.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101774629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6367 (Electronic) Linking ISSN: 26666367 NLM ISO Abbreviation: Transplant Cell Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2666-6367
DOI:10.1016/j.jtct.2025.10.023