In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery.
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| Title: | In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery. |
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| Authors: | Riedel NC; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Walter C; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.; Institute of Medical Informatics, University of Münster, Münster, Germany., de Faria FW; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Altendorf L; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Aust P; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Göbel C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Verma A; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Ballast A; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Bedzhov I; Embryonic Self-Organization research group, Max Planck Institute for Molecular Biomedicine, Münster, Germany., Roy R; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Münter D; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Schüftan E; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Albert TK; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Rössig C; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Johann P; Pediatrics and Adolescent Medicine, Swabian Children's Cancer Center, Experimental pediatrics, University Hospital Augsburg, Augsburg, Germany.; Bavarian Cancer Research Center, Augsburg, Germany., von Zezschwitz B; Department of Pediatric Hematology and Oncology, Charité University Medicine, Berlin, Germany., Sandmann S; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany., Varghese J; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany., Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Schüller U; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; 1Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bruder JM; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany., Kerl K; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany. |
| Source: | Cancer communications (London, England) [Cancer Commun (Lond)] 2025 Dec; Vol. 45 (12), pp. 1670-1675. Date of Electronic Publication: 2025 Nov 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101723675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-3548 (Electronic) Linking ISSN: 25233548 NLM ISO Abbreviation: Cancer Commun (Lond) Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2523-3548 |
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| DOI: | 10.1002/cac2.70074 |
