In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery.
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| Title: | In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery. |
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| Authors: | Riedel NC; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Walter C; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.; Institute of Medical Informatics, University of Münster, Münster, Germany., de Faria FW; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Altendorf L; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Aust P; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Göbel C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Verma A; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Ballast A; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Bedzhov I; Embryonic Self-Organization research group, Max Planck Institute for Molecular Biomedicine, Münster, Germany., Roy R; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Münter D; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Schüftan E; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Albert TK; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Rössig C; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Johann P; Pediatrics and Adolescent Medicine, Swabian Children's Cancer Center, Experimental pediatrics, University Hospital Augsburg, Augsburg, Germany.; Bavarian Cancer Research Center, Augsburg, Germany., von Zezschwitz B; Department of Pediatric Hematology and Oncology, Charité University Medicine, Berlin, Germany., Sandmann S; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany., Varghese J; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany., Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Schüller U; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; 1Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bruder JM; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany., Kerl K; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany. |
| Source: | Cancer communications (London, England) [Cancer Commun (Lond)] 2025 Dec; Vol. 45 (12), pp. 1670-1675. Date of Electronic Publication: 2025 Nov 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101723675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-3548 (Electronic) Linking ISSN: 25233548 NLM ISO Abbreviation: Cancer Commun (Lond) Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41177766 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Riedel+NC%22">Riedel NC</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Walter+C%22">Walter C</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.; Institute of Medical Informatics, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22de+Faria+FW%22">de Faria FW</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Altendorf+L%22">Altendorf L</searchLink>; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Aust+P%22">Aust P</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Göbel+C%22">Göbel C</searchLink>; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Verma+A%22">Verma A</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Ballast+A%22">Ballast A</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Bedzhov+I%22">Bedzhov I</searchLink>; Embryonic Self-Organization research group, Max Planck Institute for Molecular Biomedicine, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Roy+R%22">Roy R</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Münter+D%22">Münter D</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schüftan+E%22">Schüftan E</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Albert+TK%22">Albert TK</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Rössig+C%22">Rössig C</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Johann+P%22">Johann P</searchLink>; Pediatrics and Adolescent Medicine, Swabian Children's Cancer Center, Experimental pediatrics, University Hospital Augsburg, Augsburg, Germany.; Bavarian Cancer Research Center, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Zezschwitz+B%22">von Zezschwitz B</searchLink>; Department of Pediatric Hematology and Oncology, Charité University Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sandmann+S%22">Sandmann S</searchLink>; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Varghese+J%22">Varghese J</searchLink>; Institute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Thomas+C%22">Thomas C</searchLink>; Institute of Neuropathology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schüller+U%22">Schüller U</searchLink>; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; 1Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bruder+JM%22">Bruder JM</searchLink>; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Kerl+K%22">Kerl K</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101723675%22">Cancer communications (London, England)</searchLink> [Cancer Commun (Lond)] 2025 Dec; Vol. 45 (12), pp. 1670-1675. <i>Date of Electronic Publication: </i>2025 Nov 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101723675 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2523-3548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225233548%22">25233548 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Commun (Lond) <i>Subsets: </i>MEDLINE; In Process |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41177766 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/cac2.70074 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1670 Titles: – TitleFull: In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Riedel NC – PersonEntity: Name: NameFull: Walter C – PersonEntity: Name: NameFull: de Faria FW – PersonEntity: Name: NameFull: Altendorf L – PersonEntity: Name: NameFull: Aust P – PersonEntity: Name: NameFull: Göbel C – PersonEntity: Name: NameFull: Verma A – PersonEntity: Name: NameFull: Ballast A – PersonEntity: Name: NameFull: Bedzhov I – PersonEntity: Name: NameFull: Roy R – PersonEntity: Name: NameFull: Münter D – PersonEntity: Name: NameFull: Schüftan E – PersonEntity: Name: NameFull: Albert TK – PersonEntity: Name: NameFull: Rössig C – PersonEntity: Name: NameFull: Johann P – PersonEntity: Name: NameFull: von Zezschwitz B – PersonEntity: Name: NameFull: Sandmann S – PersonEntity: Name: NameFull: Varghese J – PersonEntity: Name: NameFull: Thomas C – PersonEntity: Name: NameFull: Schüller U – PersonEntity: Name: NameFull: Bruder JM – PersonEntity: Name: NameFull: Kerl K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2025 Dec Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2523-3548 Numbering: – Type: volume Value: 45 – Type: issue Value: 12 Titles: – TitleFull: Cancer communications (London, England) Type: main |
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