Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway.

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Title: Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway.
Authors: Maiuthed A; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Centre of Biopharmaceutical Science for Healthy Ageing, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand., Huebner K; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Erlenbach-Wuensch K; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Hampel C; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Thalheim D; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Vial-Roehe A; Department of Pathology, Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil., Nutho B; Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand., Merkel S; Department of Surgery, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Hartmann A; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Chanvorachote P; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand., Schneider-Stock R; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Adjunct Professor, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Source: Molecular oncology [Mol Oncol] 2026 Apr; Vol. 20 (4), pp. 1022-1040. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-0261
DOI:10.1002/1878-0261.70150