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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway.

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Title: Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway.
Authors: Maiuthed A; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Centre of Biopharmaceutical Science for Healthy Ageing, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand., Huebner K; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Erlenbach-Wuensch K; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Hampel C; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Thalheim D; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Vial-Roehe A; Department of Pathology, Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil., Nutho B; Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand., Merkel S; Department of Surgery, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Hartmann A; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Chanvorachote P; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand., Schneider-Stock R; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Adjunct Professor, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Source: Molecular oncology [Mol Oncol] 2026 Apr; Vol. 20 (4), pp. 1022-1040. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway.
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  Data: <searchLink fieldCode="AU" term="%22Maiuthed+A%22">Maiuthed A</searchLink>; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Centre of Biopharmaceutical Science for Healthy Ageing, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Huebner+K%22">Huebner K</searchLink>; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Erlenbach-Wuensch+K%22">Erlenbach-Wuensch K</searchLink>; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hampel+C%22">Hampel C</searchLink>; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Thalheim+D%22">Thalheim D</searchLink>; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Vial-Roehe+A%22">Vial-Roehe A</searchLink>; Department of Pathology, Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Nutho+B%22">Nutho B</searchLink>; Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Merkel+S%22">Merkel S</searchLink>; Department of Surgery, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+A%22">Hartmann A</searchLink>; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Chanvorachote+P%22">Chanvorachote P</searchLink>; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Schneider-Stock+R%22">Schneider-Stock R</searchLink>; Department of Experimental Tumor Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute of Pathology, Universitätsklinikum, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Adjunct Professor, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2026 Apr; Vol. 20 (4), pp. 1022-1040. <i>Date of Electronic Publication: </i>2025 Nov 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101308230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0261 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215747891%22">15747891 </searchLink><i>NLM ISO Abbreviation: </i>Mol Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr
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