Investigating the mechanisms of Sini San in alleviating inflammatory responses via multi-omics and the BDNF/TrkB/PI3K/AKT signaling pathway in depressive model rats.

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Title: Investigating the mechanisms of Sini San in alleviating inflammatory responses via multi-omics and the BDNF/TrkB/PI3K/AKT signaling pathway in depressive model rats.
Authors: Zeng JW; Department of Physiology, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Hubei Shizhen Laboratory, Wuhan, China.; Department of Anatomy Teaching and Research, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China., Han ZJ; Department of Physiology, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Hubei Shizhen Laboratory, Wuhan, China., He XT; Center of Monitoring and Evaluation of Teaching Quality, Jingchu University of Technology, Jingmen, China., Liu XJ; Department of Physiology, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Hubei Shizhen Laboratory, Wuhan, China., Wang HY; Department of Physiology, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Hubei Shizhen Laboratory, Wuhan, China., Yang SS; Department of Traditional Chinese Medicine, Wuhan Red Cross Hospital, Wuhan, China., Bai J; Department of English Major, School of Foreign Languages, Hubei University of Chinese Medicine, Wuhan, China., Duan YJ; Department of Anatomy Teaching and Research, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China., Lin L; Department of Physiology, College of Basic Medical Sciences, Hubei University of Chinese Medicine, Hubei Shizhen Laboratory, Wuhan, China.
Source: Frontiers in psychiatry [Front Psychiatry] 2025 Oct 17; Vol. 16, pp. 1628634. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101545006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-0640 (Print) Linking ISSN: 16640640 NLM ISO Abbreviation: Front Psychiatry Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-0640
DOI:10.3389/fpsyt.2025.1628634