Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis.

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Bibliographic Details
Title: Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis.
Authors: Tchuisseu-Kwangoua LA; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health University of Oxford Oxford UK.; HYRICCA (Hypertension et Risque Cardiovasculaire des Camerounais) Research Team, Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon., Omarov M; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany., Shatunov A; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK., Markus HS; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK., Kamtchum-Tatuene J; Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK., Georgakis MK; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany.; Program in Medical and Population Genetics and Cardiovascular Disease Initiative Broad Institute of MIT and Harvard Cambridge MA USA.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2025 Nov 04; Vol. 14 (21), pp. e041814. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2047-9980
DOI:10.1161/JAHA.124.041814