Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis.
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| Title: | Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis. |
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| Authors: | Tchuisseu-Kwangoua LA; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health University of Oxford Oxford UK.; HYRICCA (Hypertension et Risque Cardiovasculaire des Camerounais) Research Team, Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon., Omarov M; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany., Shatunov A; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK., Markus HS; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK., Kamtchum-Tatuene J; Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK., Georgakis MK; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany.; Program in Medical and Population Genetics and Cardiovascular Disease Initiative Broad Institute of MIT and Harvard Cambridge MA USA. |
| Source: | Journal of the American Heart Association [J Am Heart Assoc] 2025 Nov 04; Vol. 14 (21), pp. e041814. Date of Electronic Publication: 2025 Nov 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41182006 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tchuisseu-Kwangoua+LA%22">Tchuisseu-Kwangoua LA</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health University of Oxford Oxford UK.; HYRICCA (Hypertension et Risque Cardiovasculaire des Camerounais) Research Team, Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon.<br /><searchLink fieldCode="AU" term="%22Omarov+M%22">Omarov M</searchLink>; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Shatunov+A%22">Shatunov A</searchLink>; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK.<br /><searchLink fieldCode="AU" term="%22Markus+HS%22">Markus HS</searchLink>; Stroke Research Group, Department of Clinical Neurosciences University of Cambridge Oxford UK.<br /><searchLink fieldCode="AU" term="%22Kamtchum-Tatuene+J%22">Kamtchum-Tatuene J</searchLink>; Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK.<br /><searchLink fieldCode="AU" term="%22Georgakis+MK%22">Georgakis MK</searchLink>; Institute for Stroke and Dementia Research, LMU University Hospital LMU Munich Munich Germany.; Program in Medical and Population Genetics and Cardiovascular Disease Initiative Broad Institute of MIT and Harvard Cambridge MA USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2025 Nov 04; Vol. 14 (21), pp. e041814. <i>Date of Electronic Publication: </i>2025 Nov 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101580524 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2047-9980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479980%22">20479980 </searchLink><i>NLM ISO Abbreviation: </i>J Am Heart Assoc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41182006 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1161/JAHA.124.041814 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e041814 Titles: – TitleFull: Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tchuisseu-Kwangoua LA – PersonEntity: Name: NameFull: Omarov M – PersonEntity: Name: NameFull: Shatunov A – PersonEntity: Name: NameFull: Markus HS – PersonEntity: Name: NameFull: Kamtchum-Tatuene J – PersonEntity: Name: NameFull: Georgakis MK IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 11 Text: 2025 Nov 04 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2047-9980 Numbering: – Type: volume Value: 14 – Type: issue Value: 21 Titles: – TitleFull: Journal of the American Heart Association Type: main |
| ResultId | 1 |
