Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome.

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Bibliographic Details
Title: Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome.
Authors: Narendra VK; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Das T; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wierciszewski LJ; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Londoner RJ; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Biochemistry, Structural Biology, Cell Biology, Developmental Biology and Molecular Biology (BCMB) Allied Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Morrison JK; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology and Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Martindale P; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Devine T; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chen K; Anti-Tumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Trombetta M; Anti-Tumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kanno Y; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Casiano AE; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Stanchina E; Anti-Tumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lareau CA; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Gitlin AD; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. gitlina@mskcc.org.; Immunology and Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA. gitlina@mskcc.org.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. gitlina@mskcc.org.
Source: Nature [Nature] 2026 Jan; Vol. 649 (8099), pp. 1273-1281. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-09815-0