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Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_var.

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Title: Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_var.
Authors: Sung Y; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Yu YC; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Lee M; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Lim S; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Lee Y; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Kang M; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Kwon D; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Parajulee A; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Choi J; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Min DS; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Kim K; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Namkung W; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea., Kim YH; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Woo SM; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.; Center for Liver and Pancreatobiliary Cancer, Hospital, National Cancer Center, Goyang, 10408, Republic of Korea., Kim ND; CoBX Bio Inc., 21 Yangji-ro, Gwangmyeong-si, Gyeonggi-do, 14345, Republic of Korea., Yoo HC; College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea., Han JM; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea. jhan74@yonsei.ac.kr.; POSTECH Biotech Center, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea. jhan74@yonsei.ac.kr.
Source: Nature communications [Nat Commun] 2025 Nov 03; Vol. 16 (1), pp. 9690. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_var.
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  Data: <searchLink fieldCode="AU" term="%22Sung+Y%22">Sung Y</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+YC%22">Yu YC</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+S%22">Lim S</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+M%22">Kang M</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+D%22">Kwon D</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Parajulee+A%22">Parajulee A</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Min+DS%22">Min DS</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Namkung+W%22">Namkung W</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YH%22">Kim YH</searchLink>; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Woo+SM%22">Woo SM</searchLink>; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.; Center for Liver and Pancreatobiliary Cancer, Hospital, National Cancer Center, Goyang, 10408, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+ND%22">Kim ND</searchLink>; CoBX Bio Inc., 21 Yangji-ro, Gwangmyeong-si, Gyeonggi-do, 14345, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+HC%22">Yoo HC</searchLink>; College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+JM%22">Han JM</searchLink>; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea. jhan74@yonsei.ac.kr.; POSTECH Biotech Center, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea. jhan74@yonsei.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Nov 03; Vol. 16 (1), pp. 9690. <i>Date of Electronic Publication: </i>2025 Nov 03.
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