High level expression of glucocorticoid receptor (GR) is linked to aggressive tumor features, early biochemical recurrence, and genetic instability in prostate cancer.

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Title: High level expression of glucocorticoid receptor (GR) is linked to aggressive tumor features, early biochemical recurrence, and genetic instability in prostate cancer.
Authors: Heckmann N; Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Plage H; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Simon R; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. r.simon@uke.de., Lennartz M; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Fraune C; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Jacobsen F; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Krech T; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lebok P; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Minner S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Burandt E; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Clauditz TS; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wilczak W; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sauter G; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Gorbokon N; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Freytag M; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lutz F; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Reiswich V; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Viehweger F; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chirico V; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Heinzer H; Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Haese A; Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schlomm T; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Marx A; Department of Pathology, Academic Hospital Fuerth, Fuerth, Germany., Graefen M; Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Steurer S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bernreuther C; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ralla B; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Dum D; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hinsch A; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kind S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Luebke AM; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Menz A; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Möller K; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schlichter R; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weidemann S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Erber B; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Biernath N; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Weinberger S; Department of Urology, Charité - Universitaetsmedizin Berlin, Berlin, Germany.
Source: Prostate cancer and prostatic diseases [Prostate Cancer Prostatic Dis] 2026 Mar; Vol. 29 (1), pp. 181-188. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9815755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5608 (Electronic) Linking ISSN: 13657852 NLM ISO Abbreviation: Prostate Cancer Prostatic Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5608
DOI:10.1038/s41391-025-01046-8