IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance.
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| Title: | IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance. |
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| Authors: | Abujabal R; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany., Alanta TM; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Alhamidi RS; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Altaie AM; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Sahnoon L; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Mdkhana B; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Mahboub B; Department of Pulmonary Medicine, Rashid Hospital, Dubai, United Arab Emirates., Laumonnier Y; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany.; Airway Research Center North, Member of the, German Center for Lung Research (DZL), Lübeck, Germany., Hamoudi R; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; BIMAI-Lab, Biomedically Informed Artificial Intelligence Laboratory, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; ASPIRE Precision Medicine Research Institute Abu Dhabi, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Division of Surgery and Interventional Science, University College London, London, WC1E 6BT, UK. rhamoudi@sharjah.ac.ae., Bajbouj K; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. kbajbouj@upenn.edu., Hamid Q; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; Meakins-Christie Laboratories, McGill University, Montreal, Québec, Canada. qalheialy@sharjah.ac.ae. |
| Source: | Respiratory research [Respir Res] 2025 Nov 04; Vol. 26 (1), pp. 307. Date of Electronic Publication: 2025 Nov 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1465-993X |
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| DOI: | 10.1186/s12931-025-03371-x |
