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IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance.

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Title: IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance.
Authors: Abujabal R; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany., Alanta TM; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Alhamidi RS; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Altaie AM; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Sahnoon L; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Mdkhana B; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates., Mahboub B; Department of Pulmonary Medicine, Rashid Hospital, Dubai, United Arab Emirates., Laumonnier Y; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany.; Airway Research Center North, Member of the, German Center for Lung Research (DZL), Lübeck, Germany., Hamoudi R; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; BIMAI-Lab, Biomedically Informed Artificial Intelligence Laboratory, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; ASPIRE Precision Medicine Research Institute Abu Dhabi, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Division of Surgery and Interventional Science, University College London, London, WC1E 6BT, UK. rhamoudi@sharjah.ac.ae., Bajbouj K; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. kbajbouj@upenn.edu., Hamid Q; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; Meakins-Christie Laboratories, McGill University, Montreal, Québec, Canada. qalheialy@sharjah.ac.ae.
Source: Respiratory research [Respir Res] 2025 Nov 04; Vol. 26 (1), pp. 307. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance.
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  Data: <searchLink fieldCode="AU" term="%22Abujabal+R%22">Abujabal R</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Alanta+TM%22">Alanta TM</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Alhamidi+RS%22">Alhamidi RS</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Altaie+AM%22">Altaie AM</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Sahnoon+L%22">Sahnoon L</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Mdkhana+B%22">Mdkhana B</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Mahboub+B%22">Mahboub B</searchLink>; Department of Pulmonary Medicine, Rashid Hospital, Dubai, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Laumonnier+Y%22">Laumonnier Y</searchLink>; Institute for Nutritional Medicine, University of Lübeck, Lübeck, Germany.; Airway Research Center North, Member of the, German Center for Lung Research (DZL), Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Hamoudi+R%22">Hamoudi R</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; BIMAI-Lab, Biomedically Informed Artificial Intelligence Laboratory, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; ASPIRE Precision Medicine Research Institute Abu Dhabi, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. rhamoudi@sharjah.ac.ae.; Division of Surgery and Interventional Science, University College London, London, WC1E 6BT, UK. rhamoudi@sharjah.ac.ae.<br /><searchLink fieldCode="AU" term="%22Bajbouj+K%22">Bajbouj K</searchLink>; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. kbajbouj@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Hamid+Q%22">Hamid Q</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. qalheialy@sharjah.ac.ae.; Meakins-Christie Laboratories, McGill University, Montreal, Québec, Canada. qalheialy@sharjah.ac.ae.
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              Text: 2025 Nov 04
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