Multicenter randomized phase II study of R-MPV-A chemoimmunotherapy with or without low-dose whole-brain radiotherapy for newly-diagnosed primary CNS lymphoma.

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Title: Multicenter randomized phase II study of R-MPV-A chemoimmunotherapy with or without low-dose whole-brain radiotherapy for newly-diagnosed primary CNS lymphoma.
Authors: Omuro A; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA, USA (A.O.)., DeAngelis LM; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA (L.M.D., D.C., M.R., C.G.)., Polley MC; NRG Oncology Statistics and Data Management Center, Chicago, IL, USA (M.-Y.C.P.).; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA (M.-Y.C.P.)., Correa D; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA (L.M.D., D.C., M.R., C.G.)., Wefel JS; Department of Neurology, University of Texas MD Anderson Cancer Center, Houston, TX, USA (J.S.W.)., Bovi JA; Department of Radiation Oncology, ThedaCare Regional Cancer Center, Appleton, WI, USA (J.A.B.)., Rosenblum M; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA (L.M.D., D.C., M.R., C.G.)., Corn BW; Department of Oncology, Sha'are Zedek Medical Center, Jerusalem, Israel (B.W.C.)., Aneja S; Department of Radiation Oncology, Yale University, New Haven, CT, USA (S.A.)., Grommes C; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA (L.M.D., D.C., M.R., C.G.)., Peereboom DM; Department of Medicine, Cleveland Clinic, Cleveland, OH, USA (D.M.P.)., Lallana EC; Department of Neurology, Kaiser Permanente NCI Community Oncology Research Program, Oakland, CA, USA (E.C.L.)., Werner-Wasik M; Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA, USA (M.W.-W.)., Rogers CL; Department of Radiation Oncology, Utah Cancer Specialists, West Jordan, UT, USA (C.L.R.)., Iwamoto FM; Department of Neurology, Columbia University Minority Underserved NCORP, Manhattan, NY, USA (F.M.I.)., Yu HM; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA (H.-H.M.Y.)., Donnelly ED; Department of Radiation Oncology, Northwestern University, Evanston, IL, USA (E.D.D.)., Struve TD; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA (T.D.S.)., Won M; NRG Oncology Statistics and Data Management Center, Philadelphia, PA, USA (M.W.)., Mehta MP; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA (M.P.M.).
Source: Neuro-oncology [Neuro Oncol] 2026 Feb 01; Vol. 28 (2), pp. 371-382.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1523-5866
DOI:10.1093/neuonc/noaf221