Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.

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Title: Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.
Authors: Wu JT; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA., Imamura J; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA., Nowak E; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA., Leng J; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Reith J; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA., Kilpatrick S; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA., Schwartz GK; Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Cleveland, OH, USA., Burke ZDC; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.; Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Source: Immunotherapy [Immunotherapy] 2025 Oct; Vol. 17 (15), pp. 1079-1084. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-7448 (Electronic) Linking ISSN: 1750743X NLM ISO Abbreviation: Immunotherapy Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1750-7448
DOI:10.1080/1750743X.2025.2582518