Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.

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Title: Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.
Authors: Wu JT; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA., Imamura J; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA., Nowak E; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA., Leng J; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Reith J; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA., Kilpatrick S; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA., Schwartz GK; Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Cleveland, OH, USA., Burke ZDC; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.; Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Source: Immunotherapy [Immunotherapy] 2025 Oct; Vol. 17 (15), pp. 1079-1084. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-7448 (Electronic) Linking ISSN: 1750743X NLM ISO Abbreviation: Immunotherapy Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.
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  Data: <searchLink fieldCode="AU" term="%22Wu+JT%22">Wu JT</searchLink>; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Imamura+J%22">Imamura J</searchLink>; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Nowak+E%22">Nowak E</searchLink>; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Leng+J%22">Leng J</searchLink>; Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Reith+J%22">Reith J</searchLink>; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kilpatrick+S%22">Kilpatrick S</searchLink>; Anatomic Pathology, Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+GK%22">Schwartz GK</searchLink>; Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Burke+ZDC%22">Burke ZDC</searchLink>; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.; Genome Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.; Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
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  Data: <searchLink fieldCode="JN" term="%22101485158%22">Immunotherapy</searchLink> [Immunotherapy] 2025 Oct; Vol. 17 (15), pp. 1079-1084. <i>Date of Electronic Publication: </i>2025 Nov 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101485158 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1750-7448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221750743X%22">1750743X </searchLink><i>NLM ISO Abbreviation: </i>Immunotherapy <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1080/1750743X.2025.2582518
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        Text: English
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      – TitleFull: Remarkable response to anti-PD-L1 blockade in relapsed and refractory metastatic malignant giant cell tumor of bone: a case report.
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              M: 10
              Text: 2025 Oct
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              Y: 2025
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