Valganciclovir for cytomegalovirus viraemia in advanced HIV disease: a phase 2b randomized placebo-controlled trial of valganciclovir for cytomegalovirus viraemia in adults and adolescents with advanced HIV disease.

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Title: Valganciclovir for cytomegalovirus viraemia in advanced HIV disease: a phase 2b randomized placebo-controlled trial of valganciclovir for cytomegalovirus viraemia in adults and adolescents with advanced HIV disease.
Authors: Ellis J; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Nsangi LJ; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Rassool M; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa., Musaazi J; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Lawrence DS; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Skipper C; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Boulware DR; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Meya DB; Infectious Diseases Institute, Makerere University, Kampala, Uganda.; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.; School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda., Wasserman S; Institute for Infection and Immunity, City St George's University of London, London EC1V 0HB, UK.; Wellcome Discovery Research Platforms in Infection, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Jarvis JN; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana., Boyles T; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa.
Source: Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2025 Nov 06; Vol. 380 (1938), pp. 20240402. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Royal Society Country of Publication: England NLM ID: 7503623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2970 (Electronic) Linking ISSN: 09628436 NLM ISO Abbreviation: Philos Trans R Soc Lond B Biol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2970
DOI:10.1098/rstb.2024.0402