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Valganciclovir for cytomegalovirus viraemia in advanced HIV disease: a phase 2b randomized placebo-controlled trial of valganciclovir for cytomegalovirus viraemia in adults and adolescents with advanced HIV disease.

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Title: Valganciclovir for cytomegalovirus viraemia in advanced HIV disease: a phase 2b randomized placebo-controlled trial of valganciclovir for cytomegalovirus viraemia in adults and adolescents with advanced HIV disease.
Authors: Ellis J; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Nsangi LJ; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Rassool M; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa., Musaazi J; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Lawrence DS; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Skipper C; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Boulware DR; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Meya DB; Infectious Diseases Institute, Makerere University, Kampala, Uganda.; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.; School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda., Wasserman S; Institute for Infection and Immunity, City St George's University of London, London EC1V 0HB, UK.; Wellcome Discovery Research Platforms in Infection, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Jarvis JN; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana., Boyles T; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa.
Source: Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2025 Nov 06; Vol. 380 (1938), pp. 20240402. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Royal Society Country of Publication: England NLM ID: 7503623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2970 (Electronic) Linking ISSN: 09628436 NLM ISO Abbreviation: Philos Trans R Soc Lond B Biol Sci Subsets: MEDLINE
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  Data: Valganciclovir for cytomegalovirus viraemia in advanced HIV disease: a phase 2b randomized placebo-controlled trial of valganciclovir for cytomegalovirus viraemia in adults and adolescents with advanced HIV disease.
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  Data: <searchLink fieldCode="AU" term="%22Ellis+J%22">Ellis J</searchLink>; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Infectious Diseases Institute, Makerere University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Nsangi+LJ%22">Nsangi LJ</searchLink>; Infectious Diseases Institute, Makerere University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Rassool+M%22">Rassool M</searchLink>; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa.<br /><searchLink fieldCode="AU" term="%22Musaazi+J%22">Musaazi J</searchLink>; Infectious Diseases Institute, Makerere University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Lawrence+DS%22">Lawrence DS</searchLink>; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Skipper+C%22">Skipper C</searchLink>; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Boulware+DR%22">Boulware DR</searchLink>; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Meya+DB%22">Meya DB</searchLink>; Infectious Diseases Institute, Makerere University, Kampala, Uganda.; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.; School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Wasserman+S%22">Wasserman S</searchLink>; Institute for Infection and Immunity, City St George's University of London, London EC1V 0HB, UK.; Wellcome Discovery Research Platforms in Infection, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Jarvis+JN%22">Jarvis JN</searchLink>; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.; Botswana Harvard Health Partnership, Gaborone, Botswana.<br /><searchLink fieldCode="AU" term="%22Boyles+T%22">Boyles T</searchLink>; Clinical HIV Research Unit, a division of the Wits Health Consortium, Helen Joseph Hospital, Johannesburg 2193, South Africa.
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  Data: <searchLink fieldCode="JN" term="%227503623%22">Philosophical transactions of the Royal Society of London. Series B, Biological sciences</searchLink> [Philos Trans R Soc Lond B Biol Sci] 2025 Nov 06; Vol. 380 (1938), pp. 20240402. <i>Date of Electronic Publication: </i>2025 Nov 06.
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