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Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit.

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Title: Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit.
Authors: Kobayashi K; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Mizuta S; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Ohashi Y; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Yoshida S; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Watanabe A; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Takashima H; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Kuroda H; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Tanaka K; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Iwai A; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Okuda M; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Watanabe N; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Ikuo M; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Maihara T; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center., Ueshimo T; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Usami I; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Heike T; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center., Ohshima Y; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.
Source: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2026 Jan 01; Vol. 48 (1), pp. e21-e25. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3678 (Electronic) Linking ISSN: 10774114 NLM ISO Abbreviation: J Pediatr Hematol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1536-3678
DOI:10.1097/MPH.0000000000003142