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Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit.

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Title: Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit.
Authors: Kobayashi K; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Mizuta S; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Ohashi Y; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Yoshida S; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Watanabe A; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Takashima H; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Kuroda H; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Tanaka K; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Iwai A; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Okuda M; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Watanabe N; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Ikuo M; Becton, Dickinson and Company, Biosciences, Tokyo, Japan., Maihara T; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center., Ueshimo T; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Usami I; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology., Heike T; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center., Ohshima Y; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.
Source: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2026 Jan 01; Vol. 48 (1), pp. e21-e25. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3678 (Electronic) Linking ISSN: 10774114 NLM ISO Abbreviation: J Pediatr Hematol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit.
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  Data: <searchLink fieldCode="AU" term="%22Kobayashi+K%22">Kobayashi K</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology.<br /><searchLink fieldCode="AU" term="%22Mizuta+S%22">Mizuta S</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohashi+Y%22">Ohashi Y</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+S%22">Yoshida S</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+A%22">Watanabe A</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Takashima+H%22">Takashima H</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Kuroda+H%22">Kuroda H</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology.<br /><searchLink fieldCode="AU" term="%22Tanaka+K%22">Tanaka K</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology.<br /><searchLink fieldCode="AU" term="%22Iwai+A%22">Iwai A</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology.<br /><searchLink fieldCode="AU" term="%22Okuda+M%22">Okuda M</searchLink>; Becton, Dickinson and Company, Biosciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+N%22">Watanabe N</searchLink>; Becton, Dickinson and Company, Biosciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ikuo+M%22">Ikuo M</searchLink>; Becton, Dickinson and Company, Biosciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Maihara+T%22">Maihara T</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.<br /><searchLink fieldCode="AU" term="%22Ueshimo+T%22">Ueshimo T</searchLink>; Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Usami+I%22">Usami I</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.; Pediatric Hematology and Oncology.<br /><searchLink fieldCode="AU" term="%22Heike+T%22">Heike T</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.<br /><searchLink fieldCode="AU" term="%22Ohshima+Y%22">Ohshima Y</searchLink>; Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center.
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  Data: <searchLink fieldCode="JN" term="%229505928%22">Journal of pediatric hematology/oncology</searchLink> [J Pediatr Hematol Oncol] 2026 Jan 01; Vol. 48 (1), pp. e21-e25. <i>Date of Electronic Publication: </i>2025 Nov 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9505928 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1536-3678 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210774114%22">10774114 </searchLink><i>NLM ISO Abbreviation: </i>J Pediatr Hematol Oncol <i>Subsets: </i>MEDLINE
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